Arianne is originally from the United States and received her undergraduate degree in Biochemistry from Columbia University (New York). During her PhD, she worked between the National Â鶹ÊÓƵs of Health (USA) and the University of Cambridge. Her doctoral research examined the functional effects of genetic variants in TNF-family cytokines associated with autoimmune disease and sparked her interest in computational biology. Arianne then undertook a joint post-doctoral position between the labs of Prof Gillian Griffiths and Dr John Marioni (University of Cambridge and European Bioinformatics Â鶹ÊÓƵ). Supported by an MRC Skills Development Fellowship, her work used single-cell genomics to investigate early activation of naïve T cells.
In 2022, Arianne began as an MRC Career Development Award fellow and tenure track investigator at the Babraham Â鶹ÊÓƵ. Her research combines classical immunology with single-cell genomics and computational biology, with a long-term goal of understanding how T cells assimilate signals from pathogens and the immune environment to generate an appropriate response.